OCD and dTMS
Obsessive-compulsive disorder (OCD) is a disabling illness with high rates of poor response to
conventional treatments. OCD pathophysiology is believed to involve abnormalities in cortical-striatal thalamic-cortical circuits through regions such as the dorsomedial prefrontal cortex (dmPFC). Stimulation of these regions has been found to improve symptoms. Studies on dTMS for OCD include the integration of tailored symptom provocation based on the hypothesis that activation of the relevant circuitry may increase the therapeutic effect of the dTMS.